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NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Alpha thalassemias result from deletions

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NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Alpha thalassemias result from deletionsThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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Description

Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1

Pseudogenes of this gene are located on chromosomes 7 and 20

The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins

The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins

Probable G-protein coupled receptor 101 encoded by GPR101 is an orphan G protein-coupled receptor of unknown function

NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Alpha thalassemias result from deletionsThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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