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POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging sequence-specific DNA binding and RNA

SKU: 45170863603

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USD185.00 USD224.00

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POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging sequence-specific DNA binding and RNAPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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Description

sequence-specific DNA binding and RNA polymerase II transcription factor activity

This suggests that the human gene is therefore a pseudogene

X-ray repair cross-complementing protein 5 encoded by XRCC5 is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5

This gene encodes a subunit of RNA polymerase II

Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell

POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging sequence-specific DNA binding and RNAPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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