MELK Polyclonal Antibody, 50ul Pasteur Pipets Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

This complex functions as an upstream activator of NF-kappaB signaling

Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules

It is also an important multifunctional inflammatory mediator

The protein localizes to the nucleoli and interacts with the U3 snoRNP complex

MELK Polyclonal Antibody, 50ul Pasteur Pipets Multiple alternatively spliced transcript variantsMELK (Maternal Embryonic Leucine Zipper Kinase) is a Protein Coding gene. Among its related pathways are Neuroscience. GO annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is SNRK.