TGF beta 2 Polyclonal Antibody, 100ul Immunoassays The protein encoded by MED14

The protein encoded by MED14 (mediator complex subunit 14) is a subunit of the CRSP (cofactor required for SP1 activation) complex

Mutations in this gene have been associated with congenital myasthenic syndrome

Activity of this gene has been associated with human cancer

7 putative transmembrane domains

This growth factor lacks the N-terminal signal sequence present in most of the FGF family members

TGF beta 2 Polyclonal Antibody, 100ul Immunoassays The protein encoded by MED14This gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature