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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 20ul Oligo Pool The encoded protein may be

SKU: 44294637234

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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 20ul Oligo Pool The encoded protein may beMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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Description

The encoded protein may be involved in cell survival and proliferation| and is associated with several disease states including cancer and Alzheimer's disease

and each has been shown to have human homolog(s)

This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14

and p27Kip1 (CDKN1B)

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases

p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 20ul Oligo Pool The encoded protein may beMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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