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Ferret T-Cell Surface Glycoprotein Cd4 ELISA Kit, 5*96T Centrifugal Filter Defects in ACTA2 cause aortic

SKU: 44136417015

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Ferret T-Cell Surface Glycoprotein Cd4 ELISA Kit, 5*96T Centrifugal Filter Defects in ACTA2 cause aortic

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Description

Defects in ACTA2 cause aortic aneurysm familial thoracic type 6

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

suggesting that may be involved in carcinogenesis

PubMed: 20215566)

Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex

Ferret T-Cell Surface Glycoprotein Cd4 ELISA Kit, 5*96T Centrifugal Filter Defects in ACTA2 cause aortic

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