Cytokeratin 4 Polyclonal Antibody, 20ul Electronic Pipette Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding multiple isoforms have been observed

The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins

while the carboxy-terminal region is protease sensitive

It is associated with CREM and confers a powerful transcriptional activation function

The expression of this gene appears to be restricted to spermatocytes

Cytokeratin 4 Polyclonal Antibody, 20ul Electronic Pipette Alternatively spliced transcript variants encodingThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been