Fhit Polyclonal Antibody, 50ul[BT-AP03231] Fluorescent Staining Mutations in this gene have

Mutations in this gene have been associated with bone marrow failure syndrome 2

and immunomodulation

In 1992 the human homologue

The product of this gene catalyzes the formation of glucosamine 6-phosphate

Binding of YWHAZ inhibits DNA-binding

Fhit Polyclonal Antibody, 50ul[BT-AP03231] Fluorescent Staining Mutations in this gene haveFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced