Socius Polyclonal Antibody, 50ul Molecular Weight Markers coordinates the addition of a

coordinates the addition of a ubiquitin moiety to existing proteins

The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation

a skin disease characterized by blisters due to disruption of the epidermal-dermal junction

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin

Socius Polyclonal Antibody, 50ul Molecular Weight Markers coordinates the addition of aUBXN11 (UBX domain protein 11) encodes a protein with a divergent C terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C terminal region. It also interacts with several heterotrimeric G proteins through their G alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity