LAT Polyclonal Antibody, 100ul[BT-AP04957] Cell Function Analysis REPS1 (RALBP1 associated Eps domain

REPS1 (RALBP1 associated Eps domain containing 1) encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling

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Zinc finger protein 420 encoded by ZNF420 is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis

Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN)

which is often found in patients with chronic myelogenous leukemia

LAT Polyclonal Antibody, 100ul[BT-AP04957] Cell Function Analysis REPS1 (RALBP1 associated Eps domainLinker for activation of T cells family member 1 encoded by LAT is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular