TPPP Polyclonal Antibody, 20ul Enzymes The protein is thought to

The protein is thought to be involved in cell motility

it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology

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The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein

It is a cytoplasmic protein in normal fibroblasts (PMID: 19464300)

TPPP Polyclonal Antibody, 20ul Enzymes The protein is thought toPromotes in vitro the polymerization of tubulin into double walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM: Phosphorylated by TPK II. Poor substrate for GSK3.,Belongs to the TPPP family.,subunit: May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with