EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This protein is preferentially expressed

This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)| and in addition to a role in adhesion| it may serve as an accessory molecule for IEL activation

The type I isoform encoded by ARG1

and function as ligand-activated cation channels

Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis

and dysequilibrium syndrome 3 (CMARQ3)

EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This protein is preferentially expressedEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.