Treacle Polyclonal Antibody, 100ul Bottles but unlike other family members

but unlike other family members

GO annotations related to this gene include transcription factor activity

Mutations in this gene are associated with cardiofaciocutaneous syndrome

FBN1 encodes a member of the fibrillin family of proteins

some of which are composed of multiple subunits

Treacle Polyclonal Antibody, 100ul Bottles but unlike other family membersTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.