ARSJ Polyclonal Antibody, 20ul In vitro Assessment Mutations in this gene result

Mutations in this gene result in Lesch-Nyhan syndrome or gout

Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria

The encoded kinase (casein kinase 1 gamma 1) plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

SIAH1 encodes E3 ubiquitin-protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family

This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation

ARSJ Polyclonal Antibody, 20ul In vitro Assessment Mutations in this gene resultSulfatases (EC 3. 1. 5. 6), such as ARSJ, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005