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p53(Phospho Ser378) Polyclonal Antibody, 50ul Drying & Desiccation |Hydrolysis of the deoxyribose N-glycosidic

SKU: 41124263448

4.1
USD185.00 USD214.00

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p53(Phospho Ser378) Polyclonal Antibody, 50ul Drying & Desiccation |Hydrolysis of the deoxyribose N-glycosidicThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

|Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine| and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions

This gene encodes multiple protein isoforms that differ in their inhibitory activity

CSTF1 encodes one of three subunits which combine to form cleavage stimulation factor (CSTF)

Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region

adipocyte differentiation

p53(Phospho Ser378) Polyclonal Antibody, 50ul Drying & Desiccation |Hydrolysis of the deoxyribose N-glycosidicThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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