IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos The protein localizes to the

The protein localizes to the nucleus and is down-regulated in some cancer cell lines

The protein belongs to the S10E family of ribosomal proteins

and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors

subunit:Homodimer and homotetramer via the coiled coil regions

GAB2 (GRB2 associated binding protein 2) is a member of the GRB2-associated binding protein (GAB) gene family

IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos The protein localizes to theInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.