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GPNMB Polyclonal Antibody, 100ul Live Cell Imaging which functions in diverse cellular

SKU: 40475087373

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GPNMB Polyclonal Antibody, 100ul Live Cell Imaging which functions in diverse cellularThe protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for

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Description

which functions in diverse cellular processes including proliferation

Mutations in this gene cause autosomal-recessive intellectual disability

and likely plays a role in host defense of human bowel

Two alternatively spliced transcript variants of CDKN2C

Interleukin-1 receptor-associated kinase 3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling

GPNMB Polyclonal Antibody, 100ul Live Cell Imaging which functions in diverse cellularThe protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for

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