ANXA8 Rabbit Polyclonal Antibody, 50ul Organelle Studies Variation in ferritin subunit composition

Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues

This gene is a candidate gene for Hirschsprung disease

Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

This gene encodes a member of the membrane-spanning 4A gene family

The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex

ANXA8 Rabbit Polyclonal Antibody, 50ul Organelle Studies Variation in ferritin subunit compositionThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.