PPP1R15B Polyclonal Antibody, 20ul Low-speed Centrifuges The encoded protein may function

The encoded protein may function in stress-induced cell death pathways

also known as MCLC (Mid-1-related chloride channel) or KIAA0761

This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls

MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase

Mutations in THBD are a cause of thromboembolic disease

PPP1R15B Polyclonal Antibody, 20ul Low-speed Centrifuges The encoded protein may functionPPP1R15B encodes a protein phosphatase I interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual