DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture PLAGL1 encodes a C2H2 zinc

PLAGL1 encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

Multiple alternatively spliced variants have been described for this gene

This gene encodes a member of the SWI2/SNF2 family of proteins

CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture PLAGL1 encodes a C2H2 zincThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and