ALK Polyclonal Antibody, 100ul[BT-AP00370] Purification mutations within this protein have

mutations within this protein have been associated with ageing and bone loss

A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17

they have different patterns of tissue-specific expression and thus may play different physiologic roles

probably as part of a linker structure which prevents centrosome splitting (PubMed: 18042621)

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs

ALK Polyclonal Antibody, 100ul[BT-AP00370] Purification mutations within this protein haveALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or