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MRE11(Phospho Ser264) Polyclonal Antibody, 100ul General Lab Use PLCH2 is a member of

SKU: 38586394894

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MRE11(Phospho Ser264) Polyclonal Antibody, 100ul General Lab Use PLCH2 is a member ofThis gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a

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Description

PLCH2 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave PtdIns(4

Alternative splicing results in multiple transcript variants encoding different isoforms

Belongs to the SAS10 family

although it is now believed to be a functional gene that encodes a protein

this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins

MRE11(Phospho Ser264) Polyclonal Antibody, 100ul General Lab Use PLCH2 is a member ofThis gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a

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