Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management It was suggested that kanadaptin

It was suggested that kanadaptin is an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane

Maintains myogenic progenitors pool by suppressing differentiation through down-regulation of MYOD1 and is required for satellite cell homing and PAX7 expression (PubMed: 22940113)

Protein numb homolog encoded by NUMB plays a role in the determination of cell fates during development

PubMed: 14672706

recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin

Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management It was suggested that kanadaptinInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.