CD6 Polyclonal Antibody, 100ul[BT-AP02410] Molecular Biology The protein encoded by this

The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport

Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response

Mutations in VDR are associated with type II vitamin D-resistant rickets

promotes p53/TP53 phosphorylation on ‘Ser-46' and subsequent apoptosis

CD6 Polyclonal Antibody, 100ul[BT-AP02410] Molecular Biology The protein encoded by thisCYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2D6 localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta