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CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging Glycine-rich region (GRR) appears to

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CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging Glycine-rich region (GRR) appears toCLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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Description

Glycine-rich region (GRR) appears to be a critical element in the generation of p50

An important paralog of this gene is REG3G

which are the classical zinc finger domains found in numerous nucleic acid-binding proteins

This complex plays a critical role in erythrocyte shape and deformability

Additional splice variants have also been reported

CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging Glycine-rich region (GRR) appears toCLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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