RSPO2 Polyclonal Antibody, 100ul Protein Post-translational Modification autosomal recessive osteopetrosis

autosomal recessive osteopetrosis

Certain alleles of this gene are associated with susceptibility to dental caries

it inhibits melatonin receptor 1A function through heterodimerization

This gene and the gene encoding defensin

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

RSPO2 Polyclonal Antibody, 100ul Protein Post-translational Modification autosomal recessive osteopetrosisThis gene encodes a member of the R spondin family of proteins. These proteins are secreted ligands of leucine rich repeat containing G protein coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.