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DSC2 Polyclonal Antibody, 20ul Vessels With the ability to store

SKU: 37446867083

4.0
USD111.00 USD154.00

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DSC2 Polyclonal Antibody, 20ul Vessels With the ability to storeThis gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are

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Description

With the ability to store at 2-8℃ for maximum stability

Two alternatively spliced transcripts variants that encode the same protein have been found for this gene

leading to a CBL dependent degradation of signaling proteins

Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

DSC2 Polyclonal Antibody, 20ul Vessels With the ability to storeThis gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are

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