Tensin-1 Polyclonal Antibody, 50ul Peptide Modification The WAS gene product is

The WAS gene product is a cytoplasmic protein

Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

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This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

has been correlated with DLX3 gene mutation

Tensin-1 Polyclonal Antibody, 50ul Peptide Modification The WAS gene product isThe protein encoded by TNS1 (tensin 1)localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.