ABCB5 Monoclonal Antibody(11A2), 100ul Cellular Cultivation & Health Management inclusions in skeletal muscle fibers

inclusions in skeletal muscle fibers which affects infants

MHC II antigen presentation

targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression

This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath

Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA

ABCB5 Monoclonal Antibody(11A2), 100ul Cellular Cultivation & Health Management inclusions in skeletal muscle fibersABCB5 belongs to the ATP binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.