NCF1C Rabbit Polyclonal Antibody, 20ul Drying & Desiccation TOP2A encoding this enzyme functions

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family

A pseudogene of this gene has been identified on chromosome X

• Used for various mixing applications with optional adapters

Two transcript variants encoding different isoforms have been described for this gene

NCF1C Rabbit Polyclonal Antibody, 20ul Drying & Desiccation TOP2A encoding this enzyme functionsThe neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar multi exon pseudogenes at chromosome 7q11. 23 corresponding to this gene record and GeneID: 654816. The two pseudogenes contain a dinucleotide deletion (delta GT) in exon 2 that results in a frameshift and truncation of the open reading frame