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Hamartin Polyclonal Antibody, 50ul Cell Culture Flasks ARHGEF7 (Rho guanine nucleotide exchange

SKU: 36060750280

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USD185.00 USD235.00

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Hamartin Polyclonal Antibody, 50ul Cell Culture Flasks ARHGEF7 (Rho guanine nucleotide exchangeTSC1 (tuberous sclerosis 1) encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

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Description

ARHGEF7 (Rho guanine nucleotide exchange factor 7) encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP

is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation

Alternatively splicing results in multiple transcript variants| including the DM20 splice variant

which regulates glucose uptake and release

5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling

Hamartin Polyclonal Antibody, 50ul Cell Culture Flasks ARHGEF7 (Rho guanine nucleotide exchangeTSC1 (tuberous sclerosis 1) encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

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