LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis This locus was identified as

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome

leads to ciliary neurotrophic factor deficiency

This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus

in the chromosome 17q21 region

which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade

LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis This locus was identified asThe protein encoded by this gene is a tumor suppressor with lowered expression levels found in gastric renal colorectal lung and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.