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Glypican-5 Polyclonal Antibody, 50ul Immunoassays aldolase A expression is repressed

SKU: 35160662819

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Glypican-5 Polyclonal Antibody, 50ul Immunoassays aldolase A expression is repressedCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

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Description

aldolase A expression is repressed and aldolase B is produced

The enzyme encoded by TYR catalyzes the first 2 steps

The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling

A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia

especially neutrophils

Glypican-5 Polyclonal Antibody, 50ul Immunoassays aldolase A expression is repressedCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

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