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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage This gene is widely expressed

SKU: 35113660564

4.4
SEK141.00 SEK166.00

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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage This gene is widely expressedAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions

Inhibitor of PPP1CA

that is cleaved to yield two peptides

Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes

The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome

Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage This gene is widely expressedAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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