FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody, 50ul Cell Culture Plates The protein encoded by this

The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation| tRNA acetylation| the biosynthesis of 18S rRNA| and the enhancement of nuclear architecture and chromatin organization

and may be an important regulator of embryonic development

This gene encodes a member of the GXGD family of aspartic proteases| which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions| as well as a member of the signal peptide peptidase-like protease (SPPL) family

IV and III are shorter

tissue specificity:Highly expressed in placenta

FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody, 50ul Cell Culture Plates The protein encoded by thisdisease: A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. Translocation t(6; 11)(q21; q23) with MLL HRX. Transcriptional activator which triggers apoptosis in the absence of survival factors including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'