NGFR p75 Monoclonal Antibody, 100ul Sample Library Tubes This heterodimer binds E-box enhancer

This heterodimer binds E-box enhancer elements upstream of Period (PER1| PER2| PER3) and Cryptochrome (CRY1| CRY2) genes and activates transcription of these genes

suggesting a role as a transcription factor

Deficiency of this enzyme may contribute to hepatic dysfunction

May be a putative tumor suppressor protein

Two transcript variants encoding distinct isoforms have been identified

NGFR p75 Monoclonal Antibody, 100ul Sample Library Tubes This heterodimer binds E-box enhancerNerve growth factor receptor contains an extracellular domain containing four 40 amino acid repeats with 6 cysteine residues at conserved positions followed by a serine threonine rich region, a single transmembrane domain, and a 155 amino acid cytoplasmic domain. The cysteine rich region contains the nerve growth factor binding domain.