IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling In the nucleus

In the nucleus

The conserved helix-loop-helix ubiquitous kinase

Hsp27 is involved with cell growth and differentiation

which activates the enzyme

The encoded protein contains six extracellular cadherin domains| a transmembrane domain| and a cytoplasmic tail differing from those of the classical cadherins

IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling In the nucleusThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been