OAT1 Polyclonal Antibody, 50ul[BT-AP12160] Human Genome Knockout Libraries Transcription factor Spi-C encoded by

Transcription factor Spi-C encoded by SPIC regulates the development of red pulp macrophages

Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters

They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins

A related pseudogene has been identified on chromosome 12

The encoded protein binds calcium and is activated by myosin light chain kinase

OAT1 Polyclonal Antibody, 50ul[BT-AP12160] Human Genome Knockout Libraries Transcription factor Spi-C encoded bySolute carrier family 22 member 6 encoded by SLC22A6 is involved in the sodium dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.