TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This gene encodes a serine

This gene encodes a serine protease expressed exclusively in the thymus

Found in a complex with DNMT3A and HDAC7

FABPs may play roles in fatty acid uptake

Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This gene encodes a serineAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen