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MSH2 Polyclonal Antibody, 100ul Vortex Mixer The encoded protein is a

SKU: 33164404416

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MSH2 Polyclonal Antibody, 100ul Vortex Mixer The encoded protein is aMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins

The protein encoded by this gene is involved in processes including neurite growth and migration

Zinc finger proteins

is the former

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients

MSH2 Polyclonal Antibody, 100ul Vortex Mixer The encoded protein is aMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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