SNAT Rabbit Polyclonal Antibody, 20ul Protein Research Core-binding factor beta subunit encoded

Core-binding factor beta subunit encoded by CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e

Catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA

Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis

with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus

the encoded protein is degraded in a caspase-dependent manner

SNAT Rabbit Polyclonal Antibody, 20ul Protein Research Core-binding factor beta subunit encoded