CENPR Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification the encoded protein is associated

the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation

The encoded protein may play a role in DNA repair and mitochondrial function

The TRIM family is characterized by a signature motif composed of a RING finger| one or more B-box domains| and a coiled-coil region

their genes are pseudogenes

tissue specificity:Appears to be expressed ubiquitously

CENPR Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification the encoded protein is associatedThis gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF kappaB dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2 mediated signaling pathway. This protein is also a component of the centromere specific histone H3 variant nucleosome