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MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays RAB1B functions in the early

SKU: 32343231247

4.7
SEK162.00 SEK184.00

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MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays RAB1B functions in the earlyThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation

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Description

RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi

This gene encodes a member of the G protein-coupled receptor superfamily

which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins

Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor

This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator

MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays RAB1B functions in the earlyThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation

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