PPME1 Polyclonal Antibody, 100ul Biomatrix In mice and rats

In mice and rats

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family

Three splice variants that encode different isoforms have been identified for this gene

A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta

PPME1 Polyclonal Antibody, 100ul Biomatrix In mice and ratsThis gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase 2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.