SAFB2 Rabbit Polyclonal Antibody, 100ul Glassware The protein localizes predominantly to

The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm

Four transcript variants encoding distinct isoforms have been identified for ALDH1A2

which is a subunit of the transcription factor B (SIII) complex

SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha and CAB39

and auxiliary subunits alpha-2/delta

SAFB2 Rabbit Polyclonal Antibody, 100ul Glassware The protein localizes predominantly toThe protein encoded by this gene along with its paralog (scaffold attachment factor B1) is a repressor of estrogen receptor alpha. The encoded protein binds scaffold matrix attachment region (S MAR) DNA and is involved in cell cycle regulation apoptosis differentiation the stress response and regulation of immune genes.