Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 20ul Stepper The gene product is a

The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme

this protein interacts with and phosphorylates BRCA1

It has histone deacetylase activity and represses transcription when tethered to a promoter

which is found to encode an expanded glutamine tract in cases of Huntington's disease

Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas

Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 20ul Stepper The gene product is aHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.