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CD110 Polyclonal Antibody, 100ul[BT-AP01341] Monoclonal Antibodies This gene encodes a member

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CD110 Polyclonal Antibody, 100ul[BT-AP01341] Monoclonal Antibodies This gene encodes a memberIn 1990 an oncogene, v mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c mpl, was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony

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Description

This gene encodes a member of the annexin family

Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process

Mutations in this gene are associated with lung cancer

Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

CD110 Polyclonal Antibody, 100ul[BT-AP01341] Monoclonal Antibodies This gene encodes a memberIn 1990 an oncogene, v mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c mpl, was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony

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