Phospho-BLNK (Y84) Polyclonal Antibody, 100ul Miscellaneous Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been observed for this gene

Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene

Biochemical studies have identified additional binding partners

This gene encodes an enzyme that belongs to the methyltransferase family

This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents

Phospho-BLNK (Y84) Polyclonal Antibody, 100ul Miscellaneous Alternatively spliced transcript variants encodingBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia