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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression CDKN2A is frequently mutated or

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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression CDKN2A is frequently mutated orThe protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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Description

CDKN2A is frequently mutated or deleted in a wide variety of tumors

while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL)

An important paralog of this gene is ZSCAN10

which translates mitochondrial genes

MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP

NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression CDKN2A is frequently mutated orThe protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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