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Manic Fringe Polyclonal Antibody, 20ul Digital Burette which regulates diverse physiologic processes

SKU: 29586029991

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Manic Fringe Polyclonal Antibody, 20ul Digital Burette which regulates diverse physiologic processesMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked

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which regulates diverse physiologic processes

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the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus)

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which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons

Manic Fringe Polyclonal Antibody, 20ul Digital Burette which regulates diverse physiologic processesMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked

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